TEAM

Henry J. Donahue, Ph.D

BME Professor and Chair

Dr. Donahue is the Alice T. and William H. Goodwin, Jr. Endowed Professor and Chair Department of Biomedical Engineering and Co-Director, Institute for Engineering and Medicine  at Virginia Commonwealth University. He received his Ph.D. in Biology from the University of California, Santa Barbara and completed a post-doctoral fellowship at the Mayo Clinic. He has over 30 years of experience studying musculoskeletal biology, using both in vitro and in vivo models. His research focuses on understanding the mechanism by which bone and muscle adapt to their mechanical environment; examining the effects of space flight on musculoskeletal tissues and exploiting biophysical signals, including shear stress and nanotopography, to develop innovative strategies to regenerate musculoskeletal tissue lost to disease, injury or ageing. His research has been continually funded by the National Institutes of Health for over 30 years and he has had funding from the Department of Defense, NASA/National Space Biology Research Institute, private foundations and industry. Dr. Donahue is a fellow of the American Association for the Advancement of Science, the American Institute for Medical and Biological Engineering, the American Society of Bone and Mineral Research and the Orthopaedic Research Society.

Email: hjdonahue@vcu.edu
Phone: (804) 828-7958
Twitter: @HenryJDonahue1

Yue Zhang, Ph.D

Research Associate Professor

Yue received his PhD in Molecular Genetics from University of Pavia, Italy.  His research topics include bone biology and regeneration, cartilage biology and animal models of musculoskeletal conditions.

Email: yzhang29@vcu.edu
Phone: (804) 828-0870

Michael A Friedman, Ph.D

TRISH Postdoctoral Fellow

Michael is a TRISH postdoctoral fellow who received his PhD and Masters in biomedical engineering from Michigan University. Michael received his bachelor’s degree from University of Texas at Austin in biomedical engineering as well. His research focuses on interactive effects of exercise and nutrition on the musculoskeletal system. He is interested in studying ways to maximize bone mass and bone strength as well as ways of preventing bone loss from disuse or disease. His TRISH postdoctoral fellowship is focused on studying the effects of genetic variability on unloading-induced bone and muscle loss.

Email:  mafriedman@vcu.edu
Twitter: @MAFriedmanVCU

Evan Buettmann, Ph.D

TRISH Postdoctoral Fellow 

Evan is a TRISH postdoctoral fellow in the B.E.S.T. Lab who previously received his PhD and Master’s in Biomedical Engineering at Washington University in St. Louis. There he worked in Matthew Silva’s Mechanobiology Laboratory looking at the role of osteoblast lineage cells and VEGFA in coordinating osteogenic and angiogenic processes necessary for fracture healing. Before that Evan received his B.S. in Biological Engineering from the University of Missouri-Columbia. His current TRISH funded project is investigating the role of microgravity and connexin43 deficiency on bone fracture healing.

Email: buettmanne@vcu.edu
Twitter: @EvanBuettmann

Rachel DeNapoli

BME Ph.D. Student

Rachel is a Ph.D. student studying biomedical engineering under Dr. Donahue at VCU. Her undergraduate degree was from the University of Florida in 2018 in biomedical engineering as well. Her current research involves studying the endocannabinoid system, particularly the CB1 and CB2 receptors, and how they influence bone metabolism under different loading conditions.

Email: denapolir@vcu.edu
Twitter:denapoli_rachel

 

Gabe Hoppock

BME Ph.D. Student

Gabe is a Ph.D. student studying Biomedical Engineering under Dr. Henry Donahue at VCU. He received a Bachelor’s Degree in Biomedical Engineering from Vanderbilt University in 2019. Gabe is researching the effect loading and simulated microgravity have on osteocytes, both in vitro and in vivo. Specifically, the effects these changes have on osteocyte phenotype and protein expression and the effect of osteocytic protein expression on other musculoskeletal cell types.

Email: hoppockg@vcu.edu
Twitter: @GabrielHoppock

Steven Meas

M.D./Ph.D. Student

Steven is an MD/PhD student in the Clinical and Translational Science PhD program under the supervision of Dr. Henry Donahue. He was awarded a B.Sc. in Human Biology: Neuroscience and Animal Physiology at the University of Toronto in 2016 and then completed an M.Sc. in Laboratory Medicine and Pathobiology at the University of Toronto in 2018. His research interests include regenerative medicine, tissue engineering, aging and developmental biology. He is currently investigating the role of senescence in disuse- and aging-induced bone loss.

Email: meass2@vcu.edu

Galen Goldscheitter

M.D./Ph.D. Student

Galen Goldscheitter is an MD/PhD student in the Biomedical Engineering PhD program. He was awarded a BS in Chemical Engineering and a BA in Chemistry and Biology from the University of Colorado Boulder in 2017. His past research includes acoustic contrast agent development with Dr. Andrew Goodwin at the University of Colorado. He then investigated bone disease and factor-replacement immunogenicity in hemophilia with Dr. Jason A. Taylor at Oregon Health & Science University. His research interests include aerospace medicine, orthopedics, and neuroscience. He is currently investigating the role of innervation and non-synaptic neurotransmitter release in fracture healing, disuse, and spaceflight.

Email: goldscheittg@vcu.edu

Jessica Cornthwaite

Ph.D. Student

Jessica is a Ph.D. student studying Biomedical Engineering under Dr. Henry Donahue at VCU. She received a Bachelor’s Degree from The University of Virginia in Biomedical Engineering in 2022. Jessica is currently interested in researching the connection between the brain and bone, specifically in the context of understanding the effects of neurological disorders on bone health.

Email: cornthwaitejr@vcu.edu

Yasmina Zeineddine

Research Assistant

Yasmina received her B.S. in biomedical engineering from VCU in 2022. She has been working in the B.E.S.T. lab since September 2019. Yasmina is interested in investigating the effects of microgravity and spaceflight on muscle and bone homeostasis.

Email: zeineddinejy@vcu.edu

Lovell Abraham

Chemistry Undergraduate Student

Lovell is an undergraduate student in his senior year, majoring in Chemistry. He has been working in the B.E.S.T. Lab since March of 2020. Lovell is interested in investigating systemic bone and muscle loss during fracture healing in mice.

Email: labraham2@vcu.edu

Joseph Denisco

BME Undergraduate Student

Joseph is an undergraduate student in his junior year, majoring in biomedical engineering. He has been working at B.E.S.T. lab since October 2020 and is interested in investigating the effects of Cx43 deletion in osteocytes and bone regulation.
Email: deniscoja@vcu.edu
LinkedIn: linkedin.com/in/joseph-denisco-9464861b7

Gabriella Daire

Biology Undergraduate Student

Gabriella is an undergraduate student in her junior year. She is majoring in biology with a minor in chemistry. She has been a part of the B.E.S.T lab since August 2021. Her current research interest includes the role of senescence in the context of age and disuse related bone loss. After completing her undergraduate degree, Gabriella plans to pursue a biomedical sciences PhD program and ultimately wants a career in space medicine research
Email: dairegm@vcu.edu

Zhane Davis

Biology Undergraduate Student

Zhane is an undergraduate student in her senior year majoring in biology. She has been a part of the B.E.S.T lab since September 2022. Her research interests include how genetic variability affects the musculoskeletal response to disuse.

Jupjowt Singh

BME Undergraduate Student

Jupjowt is an undergraduate student in his sophomore year majoring in biomedical engineering. He has been a part of the B.E.S.T. lab since September 2022 and is interesting in going to medical school and specializing in orthopedics.

Sai Kathuroju

BME Undergraduate Student

Sai is an undergraduate student in his freshman year majoring in biomedical engineering. He has been a part of the B.E.S.T. lab since September 2022. His research interests include looking at how Cx43 and beta-catenin are involved in the regulation of disuse-induced bone loss.

                                                          BEST Lab Alumni

Seyed Mohsen Latifi, Ph.D.

Postdoctoral Fellow – ECPI, Lecturer

Camilla Reina Maroni, Ph.D.

Doctoral Candidate – GSK, Scientific Advisor

Otto J. Juhl IV

Doctoral Candidate – GSK, Discovery Project Manager

Christopher Brunkhorst

Undergraduate Researcher – Cornell University, Doctoral Candidate 

Ravi Shankar

Undergraduate Researcher – Johns Hopkins University, Masters Student

Anna-Blessing Merife

Undergraduate Researcher – Syracuse University, Doctoral Student

Ushna Aroura

Undergraduate Researcher – Stryker, R&D Intern

Caleb Ryan

Undergraduate Researcher – 

Wesam Elhawabri

Undergraduate Researcher –